Grace Earns Quality Certification for Pharmaceutical Manufacturing 18 Mar 2010: Grace & Co. has earned Good Manufacturing Practices (GMP) certification of its facility in Baltimore, Maryland. The certification encompasses Grace’s Quality Management System that includes the standards, procedures and manufacturing operations used by the company in the production of pharmaceutical grade silica (commonly marketed by Grace under the SYLOID® brand name). Grace Davison Discovery Sciences
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Novus Biologicals Launches First TMEM97 Antibody on the Market 16 Mar 2010: The two new antibodies are a human TMEM97 antibody and mouse TMEM97 antibody. The human TMEM97 antibody has been successfully tested in Western blot and immunocytochemistry, and the mouse TMEM97 antibody is useful for Western blot with immunocytochemistry evaluation pending. TMEM97 has been linked to several cancers including breast, pancreatic, colorectal and ovarian cancers. Novus Biologicals, LLC
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Varian Announces Next Generation Dissolution Apparatus 08 Mar 2010: Varian, Inc. announces the availability of its next generation dissolution apparatus designed for testing tablets, capsules and other dosage forms. The 708-DS supports a broad set of applications ranging from manual dissolution testing to automated, high-throughput analysis. Varian Inc
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Live Cell Imaging of Drug Effects on Golgi Morpholgy Using the CELLview™ Cell Culture Dish 01 Mar 2010: This application note by Greiner Bio-One shows that performing live-cell imaging experiments in parallel in CELLview™ dishes with four compartments allows a direct comparison of the speed and timing of drug effects on the Golgi apparatus. GalNAc-GFP cells can be easily imaged at multiple positions without cell death or focus problems. Greiner Bio-One GmbH
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Metrohm Announces New Brochure and Website «Pharmaceutical Analysis»
22 Feb 2010: Metrohm’s new brochure «Pharmaceutical analysis» is a highly valuable compendium to get an overall view of the most important parameters determining the quality of pharmaceuticals and the methods best suited to check them. Metrohm AG
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Protein/Drug Interaction: Ferulic Acid and Bovine Serum Albumin 22 Feb 2010: SPR has been demonstrated to be a powerful optical technique for bioaffinity studies at the solid/solution interface. This application note describes the kinetic studies of ferulic acid and bovine serum albumin (BSA) pre-immobilized onto an alkanethiol self-assembled monolayer (SAM)-modified gold sensor chips. Biosensing Instrument
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Establishing a Cell Culture Assay Based on Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) for Screening G-Protein Coupled Receptors 09 Feb 2010: Time-resolved fluorescence resonance energy transfer (TR-FRET) has become a popular technique in the field of high-throughput screening. This application note demonstrates the TR-FRET kit from Cisbio, the IP-One HTRF assay, under standard high-throughput screening conditions. The IP-One HTRF assay was shown to be a stable cell culture time-resolved fluorescence assay for screening G-Protein coupled receptors. Greiner Bio-One GmbH
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Tag-lite®: New HTRF® Cellular Platform for Cell Surface Receptors’ Study and Screening 09 Feb 2010: In a recent publication, Maurel et al presented the combination of Cisbio’s HTRF and SNAP-and CLIP- Tag technologies to investigate cell-surface protein-protein interaction. In this study, an application for GPCR oligomerization was accurately documented and the advantages of using the Cisbio HTRF-based cell-surface receptor platform presented. Applications such as highly selective and non-radioactive ligand binding assays are described and the 7TM dimerization model can properly be inv Cisbio Bioassays
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Analytica Announces InnovationArea - Start-ups in the spotlight 08 Feb 2010: Analytica will continue its initiative for new companies again in 2010. From March 23 – 26, 2010, international start-ups and research organizations in the biotechnology sector will present their business ideas and document the importance of the life sciences in a special area known as the InnovationArea. Messe Munchen International
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AB SCIEX Launches as New Company to Extend Leadership in Analytical Science 04 Feb 2010: AB SCIEX today launched as a new company dedicated to life science analytical technologies. The new company combines the two halves of the highly successful AB SCIEX mass spectrometry joint venture into an integrated organization. AB SCIEX
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