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News Archive
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Tag-lite®: New HTRF® Cellular Platform for Cell Surface Receptors’ Study and Screening 09 Feb 2010: In a recent publication, Maurel et al presented the combination of Cisbio’s HTRF and SNAP-and CLIP- Tag technologies to investigate cell-surface protein-protein interaction. In this study, an application for GPCR oligomerization was accurately documented and the advantages of using the Cisbio HTRF-based cell-surface receptor platform presented. Applications such as highly selective and non-radioactive ligand binding assays are described and the 7TM dimerization model can properly be inv Cisbio Bioassays
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Development of Eg5 using the HTRF Transcreener ADP kit
10 Oct 2008: Based upon Cisbio Bioassays' patented HTRF technology, HTRF Transcreener ADP assay is a universal method for identifying and characterizing the phosphotransferase activity induced by ATPases and kinases. ADP is directly detected by a specific monoclonal antibody labeled with Eu3+ Cryptate, and correlates closely with the amount of phosphorylated substrate in kinase assay. Here we describe a typical 4-step-development with the Eg5 ATPase using the HTRF Transcreener ADP assay. Cisbio Bioassays
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